Biopharma Services

Perfect Partner for Your Cancer Drug Development

Creatv Bio has developed a liquid biopsy test shown to effectively measure drug or vaccine response in patients undergoing all types of treatment, including immunotherapy. The test capture cancer associated cells from the blood of cancer patients, and the most common cell is called Cancer Associated Macrophage-Like cells (CAMLs).  This important test provides valuable information about cancer drug development in FDA Phase I-III clinical trials and can also be developed as a companion / complementary diagnostic (CDx).

Examples of CAMLs

Cancer Associated Cells

CAMLs are one of the most common stromal cells found in the blood of cancer patients and are present in all stages (I-IV). CAMLs are very large, ranging from 25 to 300 microns, and each cell exhibits unique morphological features. The blood test also provides information on Circulating Tumor Cells (CTCs), but CTCs are rare. 

The most common tumor types we have tested

  • Breast Prostate

  • Lung Colon

  • Melanoma Bladder

  • Kidney Endometrial

  • Pancreatic Liver

  • Ovarian Sarcoma

  • Renal H+N

Therapeutic Modalities

Creatv Bio has developed a liquid biopsy test shown to effectively measure drug or vaccine response in patients undergoing all types of treatment, including immunotherapy. The test capture cancer associated cells from the blood of cancer patients, and the most common cell is called Cancer Associated Macrophage-Like cells (CAMLs).  This important test provides valuable information about cancer drug development in FDA Phase I-III clinical trials and can also be developed as a companion / complementary diagnostic (CDx).

Creatv Bio Supports Your CRO

Creatv Bio’s biomarkers have been utilized in many FDA clinical trials. We will work closely with your CRO to complete the following steps:

Kit Preparation and Shipping

  • Special blood collection tubes

  • Specimen Shipment and Handling Instructions

  • Prepaid return label for samples

Results Reporting

  • Statistical analysis of results

  • CAML numbers and  size

  • CTCs numbers

  • Additional markers

  • Serial draws recommended as per protocol

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