WHAT IS THE STATUS OF MY CANCER?

assay

Pan Cancer Screening

We provide a simple blood test that potentially can screen for all cancers and in all stages.

For major cancers such as breast, prostate, lung, and colorectal, the detection rates are very high, over 80% in Stages I/II.

Cancer Aggressiveness Assessment

The blood test can also provide information about the aggressiveness of the cancer independent of imaging. The analysis requires high quality images of the cancer associated cells.

The features indicating aggressive cancers are listed below.  The features are independent of type of cancer or stage.

Major Features That Predict Poor Prognosis:

  • CTC number > 5
  • CTC in mitosis
  • CAML size ≥ 50 µm
  • Micronuclei (MN) in CAMLs
  • Extracellular Vesicles (EVs) budding from CAMLs
  • Debris in CAMLs
  • Micronuclei (MN) in CAMLs
  • DAPI size of CAMLs >465 µm2
  • CTC clusters
  • Presence of other types of tumor-macrophage hybrid cells (TMHCs) besides CAMLs

Patients have longer PFS and OS even if they have CTCs and CAMLs, but not those 10 features.

High Quality Tumor DNA for Sequencing

CAMLs provide whole DNA for sequencing, not fragmented ctDNA in the blood.

CAMLs become engorged after engulfing many tumor cells.  They contain much tumor DNA. This is an example of sequencing results of

  • tumor tissue

  • CAMLs

  • cfDNA

  • The number of mutations detected in CAMLs are much more than those found in tumor tissue and cfDNA in blood