Publications: Determination of Response to Therapy

• ASCO 2025: Monitoring populations of tumor-macrophage fusion cells in blood prognosticates PFS and OS in pan-metastatic cancers over 2 years

• SABCS 2023: Phase I/II study of pembrolizumab in combination with oral binimetinib in patients with unresectable locally advanced or metastatic triple-negative breast cancer

• AACR 2023: Peripheral blood biomarkers in Phase I/II study of pembrolizumab in combination with oral binimetinib in patients with unresectable locally advanced or metastatic triple-negative breast cancer

• AACR 2022:  Changes in Circulating Tumor Associated Cells Predicts Progression Free and Overall Survival in Metastatic TNBC Patients after Induction with the Anti-CCR5 Drug Leronlimab

• ASCO 2022:  Tracking changes in circulating stromal cells and circulating tumor cells predicts responsiveness of new line induction in metastatic breast cancer after 1 cycle of therapy

• ASCO 2022: Monitoring engorgement of phagocytic circulating stromal cells during chemo-radiotherapy induction predicts survival in unresectable stage 2/3 NSCLC

• SABCS 2022: Decreases in Circulating Tumor Associated Cells Predict PFS and OS in a Pooled Analysis of Phase I Clinical Trials Using SV-BR-1-GM Therapy with or without Immune Check-Point Inhibitors in Metastatic Breast Cancer Patient

• Keystone Symposium Conference: SV-BR-1-GM, a breast cancer cell line with features of dendritic cells, induces tumor regression in HLA matched Stage IV breast cancer patients

• AACR 2019: CAMLs are a circulating stromal cell subpopulation that accurately predicts resistance and progression in treatment naïve lung cancer patients receiving definitive radiotherapy

• Tri-Con 2019: Changes in the type of circulating cancer associated macrophage-like cells during and after radiation therapy is associated with progression in thoracic cancers

• ASCO 2018: Combining circulating tumor cells (CTCs) and circulating cancer associated macrophage - like cells (CAMLs) for accurately predicting responsiveness of new line therapies in late stage cancers

• ASCO 2015: Cancer associated macrophage-like cells correlate with systemic therapy and pathological stage in numerous malignancies

• AVI 2015: A Cell Based Liquid Biopsy for Immunotherapeutic Drug Development